A List of the Major Items of Equipment within the Core

Select an application topic and the appropriate equipment will open. Whenever there is a   next to the name of a given piece of equipment, please click on the thumbnail to view an image of the equipment as well as a summary of it's potential uses.

Biology Applications
 
Basic
Equipment covered in Training Class
Support
 
DNA/RNA  
Protein/Proteomics  
DNA/RNA/Protein  
Cell  
Chromatography  
Genomics  
Software  
Imaging  
Chemiluminescent Imaging  
Fluorescent Imaging  
Gel Documentation  
Molecular Imaging  
Image Quantitation/Analysis  
Other Core Facilities Applications
 
Fermentation
 
Fermentation and Cell Breakage
 
Kinetic Analysis
 
Biological Microcalorimetry
 
Surface Plasmon Resonance
 
Microscopy and Imaging
 
Microscopy
 
Histology  
Imaging
 
Neuroscience Institute  
Histology  
Imaging  
Modeling
 
Molecular Modeling
Computer based molecular modeling and molecular energy minimization methods are having a major impact on areas such as drug design, visualization of the structure of proteins and their complexes, and determination of molecular conformations
Silicon Graphics servers and workstations
 
Beowulf clusters
a group of usually identical PC computers running a Free and Open Source Software (FOSS) Unix-like operating system, such as BSD, Linux or Solaris. It is highly essential to the definition that the OS be Unix-like, and be free and open source. They are networked into a small TCP/IP LAN, and have libraries and programs installed which allow processing to be shared among them.
Dual Processor Linux workstations
 
40 dual - 1.5GHz CPU, 2 quad-CPU head node beowolf cluster computer
using Myranet interprocessor communication links supports multi-processor computations for molecular modeling that are implemented with the MPI-1 communications protocol, as well as batch parallel implementations of serial programs
24 dual 933 MHz CPU beowolf cluster computer
using gigabit ethernet interproccessor communication links uses the MOSIX modified linux kernel to support task migration and load balancing.
Software
used for visualization of molecular structure and interactions, and for quantum chemical, molecular mechanics, and molecular dynamics calculations for research use. These methods are used for determination of the structure of complex RNA viral genomes, to evaluate the factors that control biological activity of pharmaceutical agents and those that control motions in biological molecules.
Amber
"Amber" refers to two things: a set of molecular mechanical force fields for the simulation of biomolecules (which are in the public domain, and are used in a variety of simulation programs); and a package of molecular simulation programs which includes source code and demos.
Insight/Discover
Insight II is a sophisticated molecular modeling environment that provides a graphical interface to best-of-breed algorithms for molecular dynamics, homology modeling, de novo design, and electrostatics.
Gaussian 98 w/ Gausssview
a very powerful electronic structure calculation package that now includes a broad spectrum of density functional methods.
Spartan
Spartan is a tool for exploring organic, bioorganic, inorganic and organometallic chemistry by way of molecular mechanics and quantum chemical calculations, together with an array of graphical models for conveying the results of these calculations
Sybyl
SYBYL® is a suite of computational informatics software designed to enhance the drug discovery workflows and decision-making of today's computational chemists and molecular modelers.
 
Spectrometric Analysis
 
Mass Spectrometry
 
NMR Spectrometry
 
Spectroscopy
 
 

 


This information is given as a guide to the facilities and instrumentation available in the DNA/Protein Core facility at Georgia State University. If you have any concerns or thoughts about the content of this website please contact: John Houghton (404) 413-5390